Common fungal skin infections are caused by yeasts such as Candida or Malassezia furfur or dermatophytes, such as Epidermophyton,Microsporum, and Trichophyton. Many such fungi live only in the topmost layer of the epidermis stratum corneum and do not penetrate deeper. Obese people are more likely to get these infections because they have excessive skinfolds, especially if the skin within a skinfold becomes irritated and broken down intertrigo. People with diabetes tend to be more susceptible to fungal infections as well. Strangely, fungal infections on one part of the body can cause rashes on other parts of the body that are not infected. For example, a fungal infection on the foot may cause an itchy, bumpy rash on the fingers.
Candida infection of the skin: MedlinePlus Medical Encyclopedia
Itraconazole Itraconazole Itraconazole Sporanox, Janssen is a fat soluble synthetic triazole antifungal drug. It has the same mechanism of action as all azoles and prevents the formation of ergosterol necessary for the cell membranes of fungi. Studies with itraconazole commenced in and the drug was licensed in It is now off patent, although the IV and oral solution formulations are still patent protected. It interferes with fungal biosynthesis of ergosterol like all azoles, by interfering with the activity of 14alpha demethylase. Capsules are better absorbed taken with food.
Fungal Skin or Nail Infections
Read now Treatment Treatment for nail and skin conditions is often essential to prevent an infection from spreading to other parts of the body and other people. People who already have another health condition, such as diabetes, should seek prompt treatment if they develop a skin or nail infection, as it is more likely that complications will arise. Treatment for nail infections Nail infections can be challenging to resolve. Phoebe Rich of the American Academy of Dermatology AAD recommends the following three steps to treat Candida of the nails: Investigating and resolving any possible underlying medical causes. Keeping the nails dry and away from harsh substances or water, for example, by wearing gloves.
More Information General Information Areas commonly affected by fungal infections include the skin, scalp, feet, fingernails and toenails, mouth and vagina. Fungi need a warm, wet place to grow and they thrive on hot, sweaty skin, especially between your toes, in your groin and under your armpits. There are two common types of fungal skin infection; tinea and candida.